Diabetes Insipidus
Treatment information and medications
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Medically reviewed by Carina Fung, PharmD, BCPPS on December 18, 2019
Diabetes insipidus treatment
There are ways to manage the signs and symptoms of diabetes insipidus at home. Preventing dehydration is important. As long as you take all medications as prescribed and have access to plenty of water then their effects wear off, you can prevent becoming dehydrated. Carry water with you wherever you go, and make sure that you drink any time you feel thirsty. It’s also important to wear a medical alert bracelet or carry a medical alert card in your wallet. In the case that you have a medical emergency, a healthcare professional will be able to recognize your need for special treatment or consideration. The types of medical treatment[17] for diabetes insipidus vary depending on what form of the condition is present. If you have central diabetes insipidus, you may only need to increase the amount of water you drink. However, if the condition is caused by an abnormality in the pituitary gland or hypothalamus (such as a brain tumor), the abnormality will be treated first. Central diabetes insipidus that is caused by an abnormality is typically treated with a synthesized hormone called desmopressin. This medication, which can be taken as an oral tablet, nasal spray, or an injection, replaces the missing ADH (which is an antidiuretic hormone) and decreases urination. Other drugs like indomethacin and chlorpropamide can also make ADH more available in the body. If you have nephrogenic diabetes insipidus, medications like desmopressin won’t help, since the kidneys don’t respond normally to ADH in this form of diabetes insipidus. Your healthcare provider may instead prescribe a low-sodium diet to help reduce the amount of urine your kidneys make. You will also need to drink plenty of water to avoid dehydration. Treating nephrogenic diabetes insipidus with the drug hydrochlorothiazide may improve symptoms of the condition. While the drug is usually diuretic (increases urine output), it can reduce urine output in some people with nephrogenic diabetes insipidus. Gestational diabetes insipidus is generally treated with desmopressin. Primary polydipsia has no specific treatment other than decreasing fluid intake. Sometimes, this condition is related to mental illness. If this is the case, treating the underlying mental illness may relieve the symptoms of diabetes insipidus.Diabetes medication
Your provider may prescribe the following medications for diabetes insipidus:May be prescribed
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Diabetes treatment
Diabetes types 1 and 2, like all forms of diabetes, are often first treated[18] by maintaining a healthy lifestyle. This includes:- Eating a healthy diet: Focus on fruits, vegetables, lean proteins, and whole grains, and cut down on saturated fats, refined carbohydrates, and sweets.
- Getting enough exercise: Regular physical activity lowers blood sugar levels by moving glucose into the cells, where it’s used for energy. Exercise also increases sensitivity to insulin, meaning the body needs less insulin to transport sugar into cells.